Breathe Easy Early is an ORBEX study of asthma and wheezing in 5-16 months old babies. In this study, an oral bacterial extract is used in an attempt to boost the immune system to reduce viral infections and wheezing. Participants must have eczema or a parent or sibling 4 years or older with asthma. There will be weekly text surveys, monthly phone calls, and 12 visits at Children’s over 3 years for questionnaires, physical exams and 3 blood, stool and nasal sample collections. Study medication and supplies are provided, child is compensated up to $990, and $20 per visit to parents for travel expenses.
Vit-D-Kids is a study to see if taking Vitamin D helps reduce the number of asthma attacks in children, ages 6-16 years old, with asthma. Participants must have been diagnosed with asthma by a doctor and have taken asthma medication for 6 months. During this study, participants will have a physical exam, breathing and blood tests, nasal and urine sample collections, and complete questionnaires. Eight study visits at Children’s and 5 telephone calls over 12 months are required. Visits will take about an hour and calls less than 15 minutes. Asthma education, study medications and supplies are provided, child is compensated up to $800, and $10 per visit to parents for travel expenses.
MUPPITS-2 is a study to help learn if an asthma medication, given along with standard asthma care makes children, ages 6-17 years old, less likely to have asthma attacks. Participants must have a history of asthma, have had 2 or more asthma attacks in the last year, and take a high amount of medication to control their asthma. For this study, participants will receive monthly administrations of mepolizumab or placebo, a physical exam, an allergy skin test, breathing tests, and blood, nasal and urine sample collections, and complete questionnaires. At least 15 visits are required and the study will take up to 13 months. Compensation will vary per visit.
For more information on these studies or to have them come share with your group, contact Tina at (314) 286-1178 or Dr. Rivera at Rivera_K@wustl.edu.